{"id":1907,"date":"2020-04-23T08:35:37","date_gmt":"2020-04-23T08:35:37","guid":{"rendered":"https:\/\/www.medtech-strasbourg.eu\/?p=1907"},"modified":"2022-04-21T21:45:14","modified_gmt":"2022-04-21T19:45:14","slug":"covid19-spray-antivirus-bientot-disponible","status":"publish","type":"post","link":"https:\/\/nextmed.prod.strasbourg.cloud\/en\/2020\/04\/23\/covid19-spray-antivirus-bientot-disponible\/","title":{"rendered":"{COVID19} un spray antivirus bient\u00f4t disponible"},"content":{"rendered":"

Nous ne connaissons encore que peu de choses \u00e0 propos du COVID19. Nous savons en revanche que sa persistance sur diff\u00e9rents mat\u00e9riaux peut durer de quelques minutes \u00e0 plusieurs heures. Cette r\u00e9sistance sur des mati\u00e8res encore non identifi\u00e9es peut s’av\u00e9rer probl\u00e9matique, en premier lieu dans les milieux hospitaliers ou dans des lieux de forte fr\u00e9quentation. C’est l\u00e0 qu’intervient la startup SPARTHA MEDICAL…<\/strong><\/p>\n

Cr\u00e9\u00e9e en 2019, la start-up deeptech SPARTHA MEDICAL, issue des travaux de recherche de l\u2019Inserm \u00e0 Strasbourg, s\u2019appr\u00eatait \u00e0 conqu\u00e9rir le march\u00e9 hospitalier avec son spray antimicrobien. En quelques jours, la start-up s\u2019est repositionn\u00e9e sur le march\u00e9 des antiviraux, et pourrait permettre d\u2019\u00e9liminer le Covid-19 de n\u2019importe quelle surface. Un premier produit pourrait \u00eatre disponible d\u2019ici quelques mois.<\/p>\n

Au d\u00e9part, le chercheur Philippe Lavalle, de l’unit\u00e9 INSERM<\/span> <\/a>\u00ab\u00a0biomat\u00e9riaux et bio-ing\u00e9nierie\u00a0\u00bb cherchait \u00e0 cr\u00e9er un rev\u00eatement anti inflammatoire\u00a0pour r\u00e9pondre aux probl\u00e8mes d\u2019inflammation des tissus autour des implants. Il est alors apparu que ce rev\u00eatement, en couplant deux biopolym\u00e8res poss\u00e9dait \u00e9galement des propri\u00e9t\u00e9s anti-microbiennes.<\/p>\n

Un financement de l’institut Carnot-MICA va permettre un premier financement, suivi par le soutien de la commission europ\u00e9enne. La SATT-<\/a>Conectus<\/a><\/span>\u00a0<\/a>va alors rep\u00e9rer ce projet et le pousser \u00e0 maturation, ce qui va laisser place \u00e0 4 d\u00e9p\u00f4ts de brevets et une startup ; SPARTHA MEDICAL, cr\u00e9e en octobre 2019. Depuis, cette startup est accompagn\u00e9e par l’incubateur SEMIA<\/a><\/span>.<\/p>\n

Les sprays en lutte contre les maladies nosocomiales<\/h3>\n

SPARTHA MEDICAL s’attaque en priorit\u00e9 au march\u00e9 hospitalier et aux maladies nosocomiales (ndlr : infection contract\u00e9e dans un \u00e9tablissement de sant\u00e9), responsables de 4000 d\u00e9c\u00e8s en France chaque ann\u00e9e. Le secteur m\u00e9dical repr\u00e9sentant entre 20 \u00e0 25% du CA L’objectif \u00e9tant une d\u00e9contamination fiable rapide et simple d’utilisation, \u00e0 la fois sur les dispositifs m\u00e9dicaux type\u00a0cath\u00e9ters et sondes mais aussi sur des implants en tous genre ainsi que pansements. Mais elle envisage \u00e9galement d’autres secteurs d’activit\u00e9 comme l\u2019a\u00e9rospatial, la mode, l\u2019\u00e9nergie et l’environnement.<\/p>\n

Ce produit aurait d\u00fb \u00eatre commercialis\u00e9 courant du mois de mars, mais voil\u00e0 que le calendrier vient bousculer le planning de la startup. C’est alors que les Professeurs Philippe Lavalle et Lionel Limousy\u00a0 ainsi que\u00a0les docteurs Nihal Engin Vrana et Angela Mutschler se penchent sur la question de l’antiviralit\u00e9 de leur solution, au d\u00e9part sous forme de gel avant d’\u00eatre int\u00e9gr\u00e9 en spray. En changeant un composant, ils pourraient rendre le dispositif efficace contre le COVID19. Le gel, d\u00e9pos\u00e9 sur tout type de surface, \u00e9quipement et mat\u00e9riels, permet de d\u00e9poser une couche fine microm\u00e9trique :<\/p>\n

\u00ab\u00a0Il n\u2019emp\u00eache pas le virus de s\u2019y d\u00e9poser mais une fois d\u00e9pos\u00e9, il le d\u00e9truit. La surface agit pendant plusieurs heures, voire plusieurs jours. On pourrait traiter non seulement les surfaces dans un h\u00f4pital ou un Ehpad, mais \u00e9galement des \u00e9quipements de protection, ce qui permettrait de renforcer et prolonger leur efficacit\u00e9, et lutter ainsi contre la p\u00e9nurie de ces \u00e9quipements. \u00bb<\/p><\/blockquote>\n

explique Philippe Lavalle.<\/p>\n

Des financements de l’Agence Nationale de Recherche<\/h3>\n

Aussit\u00f4t les premi\u00e8res pistes engag\u00e9s, l’\u00e9quipe a fait appel \u00e0 l’Agence Nationale de Recherche<\/span> <\/a>(ANR) pour disposer d’un financement permettant de mettre au point le dispositif. Car si son utilisation contre le virus peut s’av\u00e9rer int\u00e9ressante, des \u00e9tudes sur son impact sur les cellules humaines sont encore \u00e0 d\u00e9finir de m\u00eame que les mol\u00e9cules virucides contre le COVID19. Un partenariat a \u00e9t\u00e9 \u00e9tablie entre les \u00e9quipes du Professeur Thomas Baumert de l’institut des maladies virales et l’\u00e9quipe de SPARTHA MEDICAL.<\/p>\n

Durant le temps de r\u00e9ponse de l’ANR, l’institut CARNOT-MICA a octroy\u00e9 20 000\u20ac aux instituts afin de pas perdre de temps. Au final, l’ANR financera \u00e0 hauteur de 200 000 euros sur 18 mois les recherches des scientifiques.\u00a0Cette somme sera partag\u00e9e entre le laboratoire de biomat\u00e9riaux, celui de virologie et la start-up. Le Pr. Limousy nous explique :<\/p>\n

\n

\u00ab Apr\u00e8s l\u2019identification des mol\u00e9cules antivirales non toxiques, nous ferons des films et v\u00e9rifierons si elles y conservent leur activit\u00e9 contre le virus. D\u00e8s la semaine prochaine, cinq personnes pourront retourner travailler dans le laboratoire, le projet devant mobiliser six \u00e0 dix personnes au maximum. Notre frein actuel, c\u2019est la commande des produits n\u00e9cessaires. Ils sont tr\u00e8s sp\u00e9cifiques et il n\u2019y a qu\u2019un seul fournisseur, avec des transports tr\u00e8s al\u00e9atoires actuellement. \u00bb<\/p>\n<\/blockquote>\n

Bravo \u00e0 cette p\u00e9pite du territoire Strasbourgeois !<\/p>","protected":false},"excerpt":{"rendered":"

Nous ne connaissons encore que peu de choses \u00e0 propos du COVID19. Nous savons en revanche que sa persistance sur diff\u00e9rents mat\u00e9riaux peut durer de quelques minutes \u00e0 plusieurs heures. […]<\/p>\n","protected":false},"author":2,"featured_media":1908,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"footnotes":""},"categories":[121,122],"tags":[90,169,92,63],"class_list":["post-1907","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid19","category-news","tag-covid19","tag-laboratoires","tag-nextmed","tag-strasbourg"],"acf":[],"yoast_head":"\n{COVID19} un spray antivirus bient\u00f4t disponible - 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